An international team of researchers has developed a handheld, non-invasive device that can detect biomarkers for Alzheimer’s and Parkinson’s Diseases. The biosensor can also transmit the results wirelessly to a laptop or smartphone. The team tested the device on in vitro samples from patients and showed that it is as accurate as the state of… Read More »
Strawberry consumption may reduce dementia risk for middle-aged individuals
New research from the University of Cincinnati found that daily strawberry consumption could help reduce the risk of dementia for certain middle-aged populations. The research was recently published in the journal Nutrients. Research background In 2022, UC’s Robert Krikorian, PhD, and his team published research that found adding blueberries to the daily diets of certain… Read More »
Scientists discover links between Alzheimer’s disease and gut microbiota
Researchers have discovered the link between the gut microbiota and Alzheimer’s disease. For the first time, researchers have found that Alzheimer’s symptoms can be transferred to a healthy young organism via the gut microbiota, confirming its role in the disease. The research was led by Professor Yvonne Nolan, APC Microbiome Ireland, a world leading SFI… Read More »
Researchers reveal link between Alzheimer’s and sex hormones
Alzheimer’s disease disproportionately affects women, who represent about two-thirds of those diagnosed with the late-onset type of the disease. Previous research has shown Alzheimer’s is also more severe and progresses more rapidly in women, and women with Alzheimer’s experience a steeper cognitive decline — loss of memory, attention, and the ability to communicate and make… Read More »
Future of Neurodegenerative Diseases
an indicator of potential cognitive diseases. The researchers examined a collection of almost 700 digitized images of slides with human hippocampal sections from aged brain donors to develop the histological brain age estimation algorithm. The hippocampus is known to be involved in both brain aging and age-dependent neurodegenerative diseases and thus is an ideal region… Read More »
Fungal infection in the brain produces changes like those seen in Alzheimer’s disease
Previous research has implicated fungi in chronic neurodegenerative conditions such as Alzheimer’s disease, but there is limited understanding of how these common microbes could be involved in the development of these conditions. Working with animal models, researchers at Baylor College of Medicine and collaborating institutions discovered how the fungus Candida albicans enters the brain, activates… Read More »
Large amounts of sedentary time linked with higher risk of dementia in older adults, study shows
Adults aged 60 and older who spend more time engaging in sedentary behaviors like sitting while watching TV or driving may be at increased risk of developing dementia, according to a new study by USC and University of Arizona researchers. Their study showed the risk of dementia significantly increases among adults who spend over 10… Read More »
Specialized T cells in the brain slow progression of Alzheimer’s disease
As many as 5.8 million Americans are currently living with Alzheimer’s disease, a neurodegenerative condition associated with progressive cognitive decline, including loss of memory capabilities . Protein aggregates, composed of beta-amyloid or other proteins, form in the brains of individuals with Alzheimer’s. These beta-amyloid plaques appear to be a significant contributor to the disease. St.… Read More »
New blood test gives very high accuracy to screen for Alzheimer’s disease
A new blood test called p-tau217 shows promise as an Alzheimer’s disease biomarker, and when used in a two-step workflow very high accuracy to either identify or exclude brain amyloidosis, the most important and earliest pathology. That is an innovation now presented by researchers at the University of Gothenburg, together with colleagues at University of… Read More »
Radiologists must monitor novel Alzheimer’s treatment side effect
A new article published in RadioGraphics, a journal of the Radiological Society of North America (RSNA), examines the use of monoclonal antibody therapies for treating Alzheimer disease and alerts physicians to be on the lookout for a potential side effect: amyloid-related imaging abnormalities (ARIA). Alzheimer disease is a progressive, irreversible brain disorder that slowly degrades… Read More »
Mice on a time-restricted feeding schedule had better memory and less accumulation of amyloid proteins in the brain compared to controls — ScienceDaily
One of the hallmarks of Alzheimer’s disease is disruption to the body’s circadian rhythm, the internal biological clock that regulates many of our physiological processes. Nearly 80% of people with Alzheimer’s experience these issues, including difficulty sleeping and worsening cognitive function at night. However, there are no existing treatments for Alzheimer’s that target this aspect… Read More »
Neuroscientists create new resource to improve Alzheimer’s disease research models
A new study by Indiana University School of Medicine researchers uses more genetically diverse mouse models to study the accumulation and spread of abnormal tau protein deposits in the brain — a known sign of Alzheimer’s disease and several other neurodegenerative diseases. The study’s findings, recently published in the Journal of Experimental Medicine, could lead… Read More »
Several vaccines associated with reduced risk of Alzheimer’s disease in adults 65 and older — ScienceDaily
Prior vaccination against tetanus and diphtheria, with or without pertussis (Tdap/Td); herpes zoster (HZ), better known as shingles; and pneumococcus are all associated with a reduced risk for developing Alzheimer’s disease, according to new research from UTHealth Houston. A pre-press version of a study was published online recently in the Journal of Alzheimer’s Disease. It… Read More »
Wildfires and farming activities may be top sources of air pollution linked to increased risk, cases of dementia — ScienceDaily
No amount of air pollution is good for the brain, but wildfires and the emissions resulting from agriculture and farming in particular may pose especially toxic threats to cognitive health, according to new research from the University of Michigan. Increasingly, evidence shows exposure to air pollution makes the brain susceptible to dementia. And now the… Read More »
Potential new tool for early identification of dementia risk — ScienceDaily
Research at the Florida State University College of Medicine has identified a potential low-cost method for predicting if a person is at risk of developing dementia. By analyzing data from nearly 13,000 subjects who participated in a long-term aging study, researchers found that an interviewer’s rating of a cognitively healthy person’s memory successfully predicted the… Read More »
Research into aromas while sleeping sparks 226% cognitive increase — ScienceDaily
When a fragrance wafted through the bedrooms of older adults for two hours every night for six months, memories skyrocketed. Participants in this study by University of California, Irvine neuroscientists reaped a 226% increase in cognitive capacity compared to the control group. The researchers say the finding transforms the long-known tie between smell and memory… Read More »
FDA-approved Alzheimer’s drug lecanemab could prevent free-floating amyloid beta fibrils from damaging the brain — ScienceDaily
For the first time, researchers described the structure of a special type of amyloid beta plaque protein associated with Alzheimer’s disease (AD) progression. In a report published May 10 in the journal Neuron, scientists showed the small aggregates of the amyloid beta protein could float through the brain tissue fluid, reaching many brain regions and… Read More »
Power of Deep Sleep Against Alzheimer’s Disease
Disrupted sleep has previously been associated with a faster accumulation of beta-amyloid protein in the brain. Unpacking the Link between Deep Sleep and Memory However, the new research from a team at UC Berkeley reveals that superior amounts of deep, slow-wave sleep can act as a protective factor against memory decline in those with existing… Read More »
Discovery provides potential clues for Lewy body and frontotemporal dementias — ScienceDaily
Scientists at the National Institutes of Health have identified new genetic risk factors for two types of non-Alzheimer’s dementia. These findings were published in Cell Genomics and detail how researchers identified large-scale DNA changes, known as structural variants, by analyzing thousands of DNA samples. The team discovered several structural variants that could be risk factors… Read More »
Alzheimer’s proteins rise sharply in response to stress in female mice — ScienceDaily
Women are about twice as likely as men to be diagnosed with Alzheimer’s disease. Some of that is age; in the U.S., women outlive men by five to six years, and advanced age is the strongest risk factor for Alzheimer’s. But there’s more to it than that, so Alzheimer’s researchers continue to look for other… Read More »
