For the first time, researchers described the structure of a special type of amyloid beta plaque protein associated with Alzheimer’s disease (AD) progression. In a report published May 10 in the journal Neuron, scientists showed the small aggregates of the amyloid beta protein could float through the brain tissue fluid, reaching many brain regions and… Read More »
Power of Deep Sleep Against Alzheimer’s Disease
Disrupted sleep has previously been associated with a faster accumulation of beta-amyloid protein in the brain. Unpacking the Link between Deep Sleep and Memory However, the new research from a team at UC Berkeley reveals that superior amounts of deep, slow-wave sleep can act as a protective factor against memory decline in those with existing… Read More »
Discovery provides potential clues for Lewy body and frontotemporal dementias — ScienceDaily
Scientists at the National Institutes of Health have identified new genetic risk factors for two types of non-Alzheimer’s dementia. These findings were published in Cell Genomics and detail how researchers identified large-scale DNA changes, known as structural variants, by analyzing thousands of DNA samples. The team discovered several structural variants that could be risk factors… Read More »
Alzheimer’s proteins rise sharply in response to stress in female mice — ScienceDaily
Women are about twice as likely as men to be diagnosed with Alzheimer’s disease. Some of that is age; in the U.S., women outlive men by five to six years, and advanced age is the strongest risk factor for Alzheimer’s. But there’s more to it than that, so Alzheimer’s researchers continue to look for other… Read More »
A Good Night’s Sleep Potential Solution to Alzheimer’s Disease
and poor sleep accelerates harmful changes to the brain. Researchers at Washington University School of Medicine in St. Louis have identified a possible way to help break that cycle. Sleeping Pills and Alzheimer’s: A Promising Connection A small, two-night study has shown that people who took a sleeping pill before bed experienced a drop in… Read More »
Non-drug interventions for patients with Alzheimer’s are both effective and cost-effective, study shows — ScienceDaily
While new drugs to treat Alzheimer’s disease tend to receive the most public attention, many well-researched ways to care for people with dementia don’t involve medication. A new evaluation compared the cost-effectiveness of four non-drug interventions to the usual care received by people with dementia and found that the interventions not only resulted in a… Read More »
Researchers shed light on role of Tip60 enzyme in genetic disruptions that cause Alzheimer’s disease — ScienceDaily
Researchers from Drexel University have uncovered a novel regulatory mechanism in the brain that is essential for making the right kinds of proteins that promote healthy brain function, and its malfunctioning may be an early contributor of the development of Alzheimer’s disease. brain cells are continuously undergoing changes in response to environmental stimuli and to… Read More »
A large UW Medicine-Kaiser Permanente study finds modestly increased risk, with a stronger link seen among younger, healthier people — ScienceDaily
People with a recent diagnosis of atrial fibrillation (AF), the most common irregular heart rhythm, have a modestly higher risk of developing dementia than people without the condition, according to research published today. “Previous studies that have examined the link between atrial fibrillation and dementia have yielded conflicting results, and we hope that our study’s… Read More »
Findings, in mice, open up drug development possibilities for brain diseases linked to tau protein — ScienceDaily
Nearly two dozen experimental therapies targeting the immune system are in clinical trials for Alzheimer’s disease, a reflection of the growing recognition that immune processes play a key role in driving the brain damage that leads to confusion, memory loss and other debilitating symptoms. Many of the immunity-focused Alzheimer’s drugs under development are aimed at… Read More »
Eye damage in Alzheimer’s disease patients — ScienceDaily
Cedars-Sinai investigators have produced the most extensive analysis to date of changes in the retina — a layer of tissue at the back of the eye where visual information originates — and how those retinal changes correspond to brain and cognitive changes in Alzheimer’s disease patients. Their analysis, published in the peer-reviewed journal Acta Neuropathologica,… Read More »
Taking vitamin D supplements may help ward off dementia, according to a new, large-scale study. — ScienceDaily
Taking vitamin D supplements may help ward off dementia, according to a new, large-scale study. Researchers at the University of Calgary’s Hotchkiss brain Institute in Canada and the University of Exeter in the UK explored the relationship between vitamin D supplementation and dementia in more than 12,388 participants of the US National Alzheimer’s Coordinating Center,… Read More »
Researchers develop highly accurate machine learning model for early detection of mild cognitive impairment and dementia in older drivers — ScienceDaily
Using ensemble learning techniques and longitudinal data from a large naturalistic driving study, researchers at Columbia University’s Mailman School of Public Health, Fu Foundation School of Engineering and Applied Science, and Vagelos College of Physicians and Surgeons have developed a novel, interpretable and highly accurate algorithm for predicting mild cognitive impairment and dementia in older… Read More »
Can Weight Loss Predict the Risk of Alzheimer’s Disease?
The high prevalence of Alzheimer’s disease in Down syndrome is due to the triplication of chromosome 21. This chromosome contains one of the genes in charge of regulating the synthesis of amyloid beta, a short chain of amino acids that can build up in the brain and interfere with brain function, resulting in cognitive impairments… Read More »
