Boosting the activity of inhibitory interneurons in Fragile X mice reduced their hypersensitivity to sensory stimuli, according to a new Neuron study led by UCLA Health researchers. Fragile X Syndrome, which is caused by a mutation in a single gene, is the most common inherited form of intellectual disability and autism. Many people with Fragile… Read More »
Norepinephrine-producing neurons in the locus coeruleus, a small nucleus in the brainstem, have been discovered to have two distinct types of cells that connect linearly via gap junctions — novel findings that have far-reaching implications for neuropsyc — ScienceDaily
A small nucleus in the brainstem called locus coeruleus (literally the “blue spot,”) is the primary source of a major neuromodulator, norepinephrine (NE), an important mediator of the ‘fight or flight’ response in animals. However, very little is known about the local connections of this small albeit critically important group of neurons. A recent pioneering… Read More »
